CBD Research
Abstracts, Links, and Studies
The following extracts are from CBD research studies and a link is provided to the full abstract or study reference.
These studies are not conclusive, or do not provide a "cure" or any endorsement of CBD. Rather, they show promising potential in the use of CBD for a variety of various conditions.
CBD Shows Therapeutic Potential for Managing Menopause 9-15-22
High-CBD Extract (CBD-X) Downregulates Cytokine Storm Systemically and Locally in Inflamed Lungs - May 2022
"In this study ....We revealed that one of the high-CBD-extracts, termed CBD-X, had an
enhanced anti-inflammatory capacity compared to the other CBD strains.
We will show that CBD-X extract reduced the levels of the
pro-inflammatory cytokines TNF-α, IL-6 and IFN-γ while increasing the
anti-inflammatory cytokine IL-10 in primary human derived neutrophils
and T cells. In a murine model displaying systemic and local lung
inflammation, it was shown that the administration of high-CBD extract
downregulated the migration of leukocytes to the site of infection and
the development of cytokine storm and leukocyte migration, both
systemically, and locally in the lung tissues."https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149302/
Cannabidiol (CBD) in Cancer Management
Feb 2022 study-abstract excerpt
from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869992/
"Cannabidiol (CBD) is one of the main constituents of the plant Cannabis
sativa. Surveys suggest that medicinal cannabis is popular amongst
people diagnosed with cancer. CBD is one of the key constituents of
cannabis, and does not have the potentially intoxicating effects that
tetrahydrocannabinol (THC), the other key phytocannabinoid has. Research
indicates the CBD may have potential for the treatment of cancer,
including the symptoms and signs associated with cancer and its
treatment. Preclinical research suggests CBD may address many of the
pathways involved in the pathogenesis of cancers. Preclinical and
clinical research also suggests some evidence of efficacy, alone or in
some cases in conjunction with tetrahydrocannabinol (THC, the other key
phytocannabinoid in cannabis), in treating cancer-associated pain,
anxiety and depression, sleep problems, nausea and vomiting, and oral
mucositis that are associated with cancer and/or its treatment. Studies
also suggest that CBD may enhance orthodox treatments with
chemotherapeutic agents and radiation therapy and protect against neural
and organ damage. CBD shows promise as part of an integrative approach
to the management of cancer."
"Survey data indicates that cancer sufferers are using cannabis
medicinally. A cross-sectional survey in 926 patients at the Fred
Hutchinson Cancer Research Centre (Seattle) found that 66% had used
cannabis previously, with 24% of respondents having used cannabis in the
past year and 21% in the past month. Of the 24% (n = 222) of
respondents who were active users, around 75% used cannabis for physical
symptoms (pain, nausea, appetite), 63% for neuropsychiatric symptoms
(stress, coping with illness, depression/improve mood, sleep), and 26%
reported they believed cannabis was helping to treat their cancer.
Encouragingly, regardless of symptom, approximately 51% judged cannabis
to be of ‘major benefit’ and 39% of ‘moderate benefit’ [1].
An anonymous online survey of 612 US-based members of the
Breastcancer.org and Healthline.com communities with a self-reported
diagnosis of breast cancer within 5 years found that 42% used cannabis
for relief of symptoms (including pain (78%), insomnia (70%), anxiety
(57%), stress (51%) and nausea/vomiting (46%)) with 46% of the belief
that cannabis can treat the cancer itself. Of those using cannabis, 79%
had used it during treatment (systemic therapies, radiation, surgery) [2]."
Exploration of Multiverse Activities of Endocannabinoids in Biological Systems
May 2022
The current review summarizes the physiological roles attained by
endocannabinoids and their relevance in treatment and management of
several chronic diseases.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147046/
